The cropping pattern of mushrooms is characterized by a quick succession of fleshes at intervals of 6-8 days within a short duration of 6-8 weeks. Often the mushrooms are consumed fresh immediately after harvest. Thus, a specific management strategy needs to be planned for nematodes associated with this crop. Use of heat has been the most successful method of nematode control in mushroom cultivation. Biological control, if exploited, has a great potential in this crop. The possible biocontrol agents, advantageous to mushrooms are microorganisms, materials/ extracts, tolerant strains, and host resistance.