The extensive utilization of pesticides in diverse sectors presents considerable challenges to marine ecosystems, prompting the need for comprehensive measures to safeguard marine flora and fauna. Pesticides, utilized in agriculture, forestry, and aquaculture for pest management, have been linked to reproductive toxicity, declines in freshwater organism populations, and the contamination of fish intended for human consumption. These chemical substances inadvertently enter marine environments through various pathways, disrupting the delicate equilibrium of marine ecosystems. Pesticides impact marine flora by infiltrating aquatic environments, resulting in detrimental effects on phytoplankton and primary producers. Similarly, marine fauna experiences a range of adverse effects, including population declines and reproductive toxicity, as a result of pesticide contamination. Strategies such as regulatory measures, precision application techniques, conservation tillage practices, integrated pest management, education and outreach programs, and monitoring and research efforts are essential for mitigating the pesticide impact on marine ecosystems. Through the collective implementation of these strategies, it is possible to minimize the adverse effects of pesticides and promote sustainable pest management practices to protect marine flora and fauna.